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Selected content from the Animal Health and Production Compendium (© CAB International 2013). Distributed under license by African Union – Interafrican Bureau for Animal Resources.

Whilst this information is provided by experts, we advise that users seek veterinary advice where appropriate and check OIE manuals for recent changes to regulations, diagnostic tests, vaccines and treatments.

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Identity    Pathogen/s    Overview    Distribution    Distribution Map for Africa    Distribution Table for Africa    Hosts/Species Affected    Host Animals    Systems Affected    Epidemiology    Impact: Economic    Zoonoses and Food Safety    Pathology     Diagnosis    Disease Course    Disease Treatment Table    Disease Treatment    Vaccines    Prevention and Control    References    Links to Websites    OIE Reference Experts and Laboratories    Images

 

 Identity

Preferred Scientific Name
rabies
International Common Names
English
dumb rabies, furious rabies, hydrophobia, lyssa, madness, paralytic rabies, rabies
Spanish
rabia
French
rage
Russian
beshenstvo

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 Pathogen/s

rabies virus

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Overview

Rabies is caused by a neurotropic virus that is transmissible to all mammals. Birds are much less susceptible to the virus than mammals, and the presence of disease in them is very rare. The first description of rabies originates from Babylon (BC 2300). Later, Demokritos and Aristotle mentioned transmission by dogs (BC 500 and BC 400, respectively). Pasteur and his co-workers developed the first immunization method in 1885. Negri discovered the inclusion bodies named after him in 1903, and the immunofluorescence test for rabies was devised by Goldwasser and Kissling in 1958.

The importance of rabies is characterized by its worldwide distribution, fatal outcome and its zoonotic aspects. Although direct economic losses are low, costs of control and elimination of the disease from a region are very high.

This disease is on the list of diseases notifiable to the World Organisation for Animal Health (OIE). The distribution section contains data from OIE's WAHID database on disease occurrence. Please see the AHPC library for further information on this disease from OIE, including the International Animal Health Code and the Manual of Standards for Diagnostic Tests and Vaccines. Also see the website: www.oie.int.

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Distribution

Rabies occurs throughout the world and only a few countries are free of the disease, due to successful eradication programs or to island status and enforcement of rigorous quarantine regulations (Aiello and Mais, 1998; Blancou, 1998). In farm animals, rabies occurs in cattle, sheep, pigs, and horses in most countries. Bovines, including cattle and buffaloes, are the most commonly affected domestic animals (Gylys et al., 1998; Jindal and Narang, 1998; Krebs et al., 1998). Rabies in cattle is a major economic and public health problem in South America, where vampire bat-transmitted rabies results in cyclic outbreaks (Alvarez-Peralta, 1997; Jacobo et al., 1998). In Europe, sylvatic rabies is a major problem where the red fox is the principal vector; cattle are mainly infected by rabid foxes (Pastoret and Brochier, 1999; Muller et al., 1999b). More recently, bat-transmitted rabies has also been described in Europe (WHO, 1996; World Health Organization, 1998). Rabies occurs in most countries in Africa, and affects cattle and other bovines. In USA, endemic infection exists throughout southern Ohio, and the prairie states; rabies in domestic animals has steadily decreased there during the past 30 years, whereas annual occurrence in wild animals has increased (Krebs et al., 1999). Rabies is widespread and is a serious problem in several countries in Asia (Rathore, 1998), and in both European and Asian Russia. Australia and New Zealand have never had the disease (Radostits et al., 1999).

For current information on disease incidence, see OIE's WAHID Interface.

Rabies is common and enzootic in many African countries. A total of 34 countries reported 1,608 outbreaks of rabies to AU-IBAR in 2011, accounting for 7.2% of all disease outbreaks reported making it the disease with the highest number of outbreak reports. By virtue of the reports received it would appear that rabies is the most widely distributed zoonotic disease in Africa. This observation should be tempered by the fact that other zoonotic diseases are less readily diagnosed on clinical signs alone and it can be argued that many cases of for example brucellosis, echinococcosis and cysticercosis go undetected and are consequently under-reported. Algeria, South Africa and Namibia recorded the highest number of outbreaks of brucellosis with 522, 236 and 183 reports respectively (AU-IBAR, 2011).

Countries in Africa reporting rabies to AU-IBAR in 2011

CountryOutbreaksCasesDeathsSlaughteredDestroyed
Algeria5225631912476
Benin11NSNSNS
Botswana41374500
Cameroon3330NS
Central African Republic210400
Chad22012
Congo DRC18778005
Côte d'Ivoire13171715
Eritrea111NS1
Ethiopia383251874NS
Gabon33300
Gambia33300
Ghana444935015
Kenya1111601
Lesotho11212200
Liberia1151409
Madagascar399NSNS
Malawi444NSNS
Mauritania1212903
Mozambique23101
Namibia18326925300
Nigeria143010311
Rwanda4086590795
Senegal18383600
Somalia5101000
South Africa236NSNSNSNS
Sudan11100
Swaziland57625534
Tanzania1021427NSNS
Togo14256162
Tunisia10691826234
Uganda7446619111952
Zambia4220768NSNS
Zimbabwe7311492NSNS
Total (34)1608277915242111416

NS=Not specified

Although rabies is one of the major zoonotic diseases, reports on its situation from many countries are often incomplete. There were many gaps in the reports received in 2011, most of which did not capture the number of outbreaks, cases, mortalities, species involvement, sources of infection and the number of human cases. These parameters are essential to substantiate the impact of rabies in public health. Nevertheless, available data calls for an urgent, concerted and coordinated effort in controlling the disease in Africa considering its impact on human health.

Dogs were the most commonly affected species, constituting 63% of all cases followed by cattle (16%) and sheep and goats (4%). There was a high incidence of rabies cases in wildlife reported by Namibia where 59 cases of a total of 70 reported cases occurred in wildlife. The species most commonly affected were the greater kudu antelope and jackal.

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Distribution Map for Africa

Distribution Map for AfricaDistribution Map for Africa

present, no further details = Present, no further details    widespread = Widespread    localised = Localised
confined and subject to quarantine = Confined and subject to quarantine    occasional or few reports = Occasional or few reports
evidence of pathogen = Evidence of pathogen    last reported = Last reported...    presence unconfirmed = Presence unconfirmed

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 Distribution Table for Africa

The distribution in this summary table is based on all the information available. When several references are cited, they may give conflicting information on the status. Further information for individual references may be available in the Animal Health and Production Compendium. A table for worldwide distribution can also be found in the Animal Health and Production Compendium.

CountryDistributionLast ReportedOriginFirst ReportedInvasiveReferencesNotes
AFRICA
AlgeriaPresent    OIE, 2012 
AngolaPresent    OIE, 2012 
BeninPresent, no further details    OIE, 2012 
BotswanaPresent    OIE, 2012; Masupu, 1992 
Burkina FasoPresent    OIE, 2012 
BurundiPresent, no further details    OIE, 2012 
CameroonPresent, no further details    OIE, 2012 
Cape VerdeDisease never reported    OIE, 2012 
Central African RepublicPresent, no further details    AU-IBAR, 2011 
ChadPresent, no further details    AU-IBAR, 2011 
ComorosDisease never reported    OIE, 2012 
CongoNo information available    OIE, 2009 
Congo Democratic RepublicPresent, no further details    OIE, 2012 
Côte d'IvoirePresent, no further details    AU-IBAR, 2011 
DjiboutiDisease not reported    OIE, 2009 
EgyptPresent, no further details    OIE, 2012; Salem et al., 1995 
Equatorial Guinea     OIE, 2012Disease suspected
EritreaPresent, no further details    AU-IBAR, 2011 
EthiopiaPresent, no further details    OIE, 2012 
GabonPresent, no further details    AU-IBAR, 2011 
GambiaPresent, no further details    AU-IBAR, 2011 
GhanaPresent, no further details    OIE, 2012 
GuineaDisease not reported    OIE, 2009 
Guinea-Bissau     OIE, 2012Disease suspected
KenyaPresent, no further details    OIE, 2012; Muriuki et al., 1994; Binepal, 1992 
LesothoPresent    OIE, 2012; Khomari, 1992 
LiberiaPresent, no further details    AU-IBAR, 2011 
LibyaPresent, no further details    OIE, 2012 
MadagascarPresent, no further details    OIE, 2012; Morvan, 1992 
MalawiPresent    OIE, 2012; Mwiyeriwa, 1992 
MaliDisease not reported    OIE, 2009 
MauritaniaPresent, no further details    OIE, 2012 
MauritiusDisease not reported    OIE, 2012 
MoroccoPresent    OIE, 2012 
MozambiquePresent    OIE, 2012; Dias, 1992 
NamibiaPresent    OIE, 2012; Depner, 1992 
Niger     OIE, 2012Disease suspected
NigeriaPresent    OIE, 2012 
RéunionDisease never reported    OIE Handistatus, 2005 
RwandaPresent    OIE, 2012 
Sao Tome and PrincipeDisease not reported    OIE Handistatus, 2005 
SenegalPresent, no further details    OIE, 2012 
SeychellesDisease not reported    OIE Handistatus, 2005 
SomaliaPresent, no further details    OIE, 2012 
South AfricaPresent    OIE, 2012; Bishop, 1992 
SudanPresent, no further details    AU-IBAR, 2011; Hameid, 1991 
SwazilandPresent    OIE, 2012 
TanzaniaPresent    OIE, 2012; Kavishe, 1988 
TogoPresent    OIE, 2012 
TunisiaPresent    AU-IBAR, 2011; Arrouji et al., 1991 
UgandaPresent, no further details    OIE, 2012; Illango, 1992 
ZambiaPresent    OIE, 2012; Sinyangwe, 1992; Mweene et al., 1996 
ZimbabwePresent    OIE, 2012; Bingham, 1992 

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 Hosts/Species Affected

Hosts of infection can be any of the wild or domestic animals listed under the rabies virus data sheet. Ruminants, swine and horses kept outdoors under extensive husbandry systems are especially prone to infection.

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Host Animals

Animal name Context 
Bos grunniens (yaks) Domesticated host, Wild host 
Bos indicus (zebu) Domesticated host 
Bos mutus (yaks, wild) Domesticated host, Wild host 
Bos taurus (cattle) Domesticated host 
Bubalus bubalis (buffalo) Domesticated host 
Camelus dromedarius (dromedary camel) Domesticated host 
Capra hircus (goats) Domesticated host 
Capreolus capreolus Domesticated host, Wild host 
Equus caballus (horses) Domesticated host 
Lama glama (llamas) Domesticated host 
Lama pacos (alpacas) Domesticated host 
Ovis aries (sheep) Domesticated host 
Rangifer tarandus (reindeer) Domesticated host, Wild host 
Sus scrofa (pigs) Domesticated host, Wild host 

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Systems Affected

Multisystem - Large Ruminants
Multisystem - Pigs
Multisystem - Small Ruminants
Nervous - Large Ruminants
Nervous - Pigs
Nervous - Small Ruminants

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Epidemiology

The source of infection is always an infected animal, and the method of spread is almost always by the bite of an infected animal, although contamination of skin wounds by fresh saliva may result in infection. Aerosol transmission can occur under special circumstances, for example, in bat caves or in laboratories manipulating the virus. The virus may appear in the milk of infected animals, but spread by this means is not very likely. Animal vectors are numerous and their role differs according to region. Traditionally the dog, and to a lesser extent the cat, have been the main sources of infection in domestic settings. The native fauna provide the major sources of infection in countries where domestic or feral carnivores are well controlled (Muller et al., 1999). Cattle are rarely a source of infection, although transmission to humans may occur when manipulating the mouth of a rabid animal, for example, during treatment or examination (Tariq et al., 1991; Radostits et al., 1999).

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Impact: Economic

Losses from diseased animals (which invariably all die) are relatively low (Borowka, 1994). Of more significance is the value of condemned milk from infected or possibly infected cows and the expenses of preventive vaccination of animals (World Health Organization, 1989, Dufour et al., 1989), and post-infection vaccination of people (Anon., 1999; Zeller et al., 1989).

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Zoonoses and Food Safety

Zoonoses

Rabies is transmissible to humans by the inoculation (via bites, mainly from carnivores, or wounds contaminated with saliva) or inhalation (from bats) of infectious virus. Rabies in humans produces very grave central nervous system (CNS) clinical signs (Krebs et al., 1999), and has a fatal outcome in nearly all cases. This very severe illness requires skilful intensive care with attention to the airway, maintenance of oxygenation, and control of seizures.

Post-infection control of the disease should be done by vigorous first aid for bite wounds and post-exposure immunization (Zeller et al., 1989; Ostrowska and Hermanowska-Szpakowicz, 1997). Therefore, local health authorities must be consulted in all cases of suspected exposure.

Transmission in Food

The milk and meat of infected animals should be condemned. People that have accidentally consumed infected products should be vaccinated against rabies; this may be an expensive operation (Borowka, 1994; Anon., 1999).

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Pathology

The virus travels via the peripheral nerves to the spinal cord and ascends to the brain after replication within muscle cells near the site of inoculation. After reaching the brain, the virus usually travels efferently through the peripheral nerves to the salivary glands (Aiello and Mais, 1998; Singh and Grewal, 1998a).

Macroscopic findings are unremarkable, and there is no gross pathognomonic lesion for rabies. Histopathological findings are characterized by non-suppurative encephalomyelitis and ganglioneuritis, with neuronal necrosis and the formation of glial nodules. Negri bodies (aggregates of viral material in the cytoplasm of neurones) are most commonly found in the Purkinje cells of the cerebellum in ruminants (Radostits et al., 1999).

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Diagnosis

Clinical Diagnosis

In any animal, the first sign is a change in behaviour, which may be indistinguishable from a gastrointestinal disorder, injury, foreign body in the mouth, poisoning, or an early infectious disease. Temperature change is not significant and drivelling may or may not be noted. Animals usually stop eating and drinking and may seek solitude. Frequently, the urogenital tract is irritated or stimulated as evidenced by frequent urination, erection in the male, and sexual desire. After the prodromal period of 1-3 days, animals either show signs of paralysis or become vicious. Paralysis of the cranial nerves is soon obvious and commonly results in difficulties in chewing, drinking, swallowing (dyspaghia), and evidence of drooling. Dropping of the lower jaw and strabismus can often be observed.

Signs may vary with the species affected (Kandavel et al., 1989; Aiello and Mais, 1998, Stoltenow et al., 1998; Vörös et al., 1999). Cattle with furious rabies are dangerous, attacking and pursuing man and other animals; instead of the usual placid expression there is one of alertness. A common clinical sign is a characteristic abnormal bellowing. In the paralytic form, cranial nerve paralysis, especially hind leg paresis followed by paralysis of all four legs may be observed, while excitement may be missing. Finally, recumbency and death will follow. The signs in sheep and goats resemble those in cattle. In sheep, vigorous wool pulling, tremors and sudden falling can occur; however, many sheep become quiet and anorectic. Infected goats are commonly aggressive, and continuous bleating is common. Rabid swine manifest excitement and a tendency to attack, or conversely, dullness and incoordination. Rapid chewing movements and convulsions can also be present. Paralysis and death usually occurs in pigs 12-48 hours after the onset of signs, which may be extremely variable (Hou, 1992; Kociorski, 1994).

Clinical observation may only lead to a suspicion of rabies, because symptoms of the disease are not always characteristic and may vary greatly from one animal to another.

Differential Diagnosis

Several diseases, especially those affecting the nervous system, can resemble some signs of rabies (Leupold et al., 1989). The following list includes examples for farm animals (Radostits et al., 1999).

Cattle, sheep and goats

Lead poisoning, lactation tetany, polioencephalomalacia (vitamin B1 hypovitaminosis), vitamin A deficiency, listeriosis, bacterial meningoencephalitis, pseudorabies (Aujeszky's disease in cattle), enterotoxemia in sheep, pregnancy ketosis in sheep, coenurosis in sheep.

Swine

Pseudorabies, Teschen's disease, African swine fever, bacterial meningoencephalitis.

As a golden rule, in regions where the disease is present, rabies should be considered in any cases with even uncertain nervous signs or in animals found in a moribund stage or dead in outside pens or pastures, until otherwise proven.

Laboratory Diagnosis

As there is no gross pathognomonic lesion for rabies, diagnosis can only be made by laboratory techniques, preferably conducted on central nervous system (CNS) tissue previously removed from the cranium; the hippocampus (Ammon's horn) and the medulla oblongata are the tissues of choice. However, similar laboratory methods can also be applied to other organs, such as the salivary glands and cornea (Singh et al., 1999). Specimens for rabies diagnosis must be processed rapidly and sent to the laboratory under cold conditions, because rabies virus can be soon inactivated by heat (Barrat, 1992).

Diagnosis is preferably performed using the fluorescent antibody test (FAT). A drop of immune serum previously conjugated with fluorescein isothiocyanate is added to a fixed brain tissue smear, preferably made from several parts of the brain including the hippocampus and medulla oblongata (Umoh and Blenden, 1981; Barnard and Voges, 1982; Barrat, 1992). Alternatively, antibody may be conjugated to an enzyme such as peroxidase instead of fluorescein isothiocyanate (FITC). This conjugate may be used for direct diagnosis with the same sensitivity as FAT (Genovese and Andral, 1978). The immunoenzyme technique can provide rapid results when handling a large number of samples as part of an epidemiological survey. This is 'rapid rabies enzyme immunodiagnosis' (RREID), an ELISA test that detects rabies antigen (Perrin et al., 1986). Both FAT and RREID provide a reliable diagnosis in 98-100% of cases.

Histological tests can be used to demonstrate infected neuronal cells. These traditional procedures will reveal aggregates of viral material (the Negri bodies) in the cytoplasm of neurones. Nevertheless, this method does not always detect the virus (Singh and Grewal, 1998b), and the sensitivity of histological techniques depends on the degree of autolysis of the specimen; up to 15% false-negative results are observed on putrefied specimens. As a single negative test on fresh material does not rule out the possibility of infection, inoculation tests should be carried out simultaneously. Newborn mice or 3-4-week-old mice are inoculated intracerebrally with a suspension of hippocampal tissue, or a pool of several CNS tissues, and then kept under observation for 28 days. For any mouse that dies between 5 and 28 days, the cause of death should be confirmed by FAT. A neuroblastoma cell line, identified CCL131 in the American Type Culture Collection (ATCC), is used as a cell culture test for routine diagnosis of rabies. This cell line is sensitive to street isolates, but should be checked for susceptibility to locally predominant virus variants before use. Replication of rabies virus in the cells is revealed by FAT (Barrat et al., 1986). This test is as sensitive as the mouse inoculation test, but it is much cheaper and gives a more rapid result.

Serological evidence of infection is rarely obtained because of the high mortality rate of host species, although such evidence may be used in some epidemiological surveys. However, serological tests are used to assess the potency of vaccines against rabies; these are the virus neutralization test and the fluorescent antibody virus neutralization (FAVN) tests (Smith et al., 1973; Zalan et al., 1979; Perrin et al., 1985).

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Disease Course

The incubation period of naturally occurring cases is usually about 3 weeks, but can vary from 2 weeks to several months. Rabid animals of all species exhibit typical signs of central nervous system (CNS) disturbance, with minor variations peculiar to carnivores, ruminants, bats, and humans. The clinical course, particularly in dogs, can be divided into three phases: the prodromal, the excitative, and the paralytic. The term 'furious rabies' refers to animals in which the excitative phase is predominant, and 'dumb' or 'paralytic rabies' to those in which the excitative phase is extremely short or absent and the disease progresses quickly to the paralytic phase. The disease progresses rapidly after the onset of paralysis; death usually occurs within 3-6 days and is virtually certain within 10 days of the first signs (Tanyi et al., 1988; Schulz, 1989).

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Disease Treatment Table

DrugDosage, administration and withdrawal timesLife stagesAdverse affectsDrug resistanceType
Defensor (Pfizer)® 2 ml per animal (older than 3 months), given intramuscularly, withdrawal time is 21 days All Stages/All Stages  No Vaccine 
Nobivac rabies (Intervet)® 1 ml per animal (older than 6 months) given intramuscularly or subcutaneously All Stages/All Stages rarely, local swelling or anaphylactic reaction No Vaccine 
Rabisin (Merial)® 1 ml per animal (older than 4 months) given intramuscularly or subcutaneously All Stages/All Stages/All Stages  No Vaccine 
Rhabdomun (Schering Plough)® 1 ml per animal given subcutaneously All Stages/All Stages/All Stages rarely, anaphylactic reaction No Vaccine 

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Disease Treatment

No treatment should be attempted after clinical signs are evident. Euthanasia of suspect animals must be avoided, particularly if human exposure has occurred, since the development of the disease in animals is necessary to establish a diagnosis (Radostits et al., 1999). In several countries, cases of rabies in farm animals are notifiable to the animal health and disease regulatory bodies.

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Vaccines

VaccineDosage, Administration and Withdrawal TimesLife StagesAdverse Affects
Defensor (Pfizer)® 2 ml per animal (older than 3 months), given intramuscularly, withdrawal time is 21 days   
Nobivac rabies (Intervet)® 1 ml per animal (older than 6 months) given intramuscularly or subcutaneously  rarely, local swelling or anaphylactic reaction 
Rabisin (Merial)® 1 ml per animal (older than 4 months) given intramuscularly or subcutaneously   
Rhabdomun (Schering Plough)® 1 ml per animal given subcutaneously  rarely, anaphylactic reaction 

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Prevention and Control

Immunization and Vaccines

Rabies vaccines for use in animals contain either live virus attenuated for the target species (for example, Flury low egg passage, Flury high egg passage, Street-Alabama-Dufferin or Kelev), or virus inactivated by chemical or physical means, or recombinant vaccines.

Subtypes of rabies virus may vary considerably in their pathogenicity. They can be classified according to origin as vulpine, canine, etc. However, with the exception of serotype 3, their immunogenicity provides almost complete cross-protection. For animals, live vaccines are also effective by the oral route and can be distributed in baits in order to immunize wild (or domestic) animals (Kieny et al., 1984, Krebs et al., 1999). Live recombinant vaccine (for example, vaccinia rabies-glycoprotein recombinant) has also proved to be effective.

Both live and inactivated vaccines have their advantages and disadvantages (Baer, 1991), but both can be used to immunize animals for periods of between 1 and 3 years (Sihvonen et al., 1994; Basheer et al., 1997; Jenkins, 1998). They are not to be relied on to protect previously unvaccinated animals that have been exposed to infection (Blancou et al., 1991).

In addition to vaccination, prevention of exposure should be encouraged whenever is possible by vaccinating vector animals, and keeping farm animals indoors. A promising widespread oral vaccination technique distributed in baits has been used with promising results in Canada, in the USA and in Europe (World Health Organization, 1989; Krebs et al., 1999; Pastoret and Brochier, 1999).

Control of Vectors

The chemicals warfarin and diphenadione have been used to control vampire bats in South America (Delpietro et al., 1991; Sald and Flores-Crespo, 1991).

National and International Control Policy

Rabies is included on the list of notifiable diseases by the Office International des Epizooties (OIE). Strict quarantine regulation is and should be performed in countries and regions that are currently free from disease. Control of rabies is internationally organized by OIE.

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References

African Union-Interafrican Bureau for Animal Resources, 2011. Panafrican Animal Health Yearbook 2011. Pan African Animal Health Yearbook, 2011:xiii + 90 pp. http://www.au-ibar.org/pan-african-animal-health-yearbook

Aiello SE, Mais A (eds), 1998. The Merck Veterinary Manual. Whitehouse Station, NJ, USA: Merck & Co. Inc. and Merial Limited, 966-970.

Al-Qudah KM, Al-Rawashdeh OF, Abdul-Majeed M, Al-Ani FK, 1997. An epidemiological investigation of rabies in Jordan. Acta Veterinaria (Beograd), 47(2/3):129-134; 16 ref.

Alvarez-Peralta E, 1997. Rabies transmission by vampire bats - distribution, frequency and importance (in Spanish). Tecnica Pecuaria en Mexico, 35(2):93-104.

Anon., 1999. Mass treatment of humans who drank unpasteurized milk from rabid cows - Massachusetts, 1996-1998. Morbidity and Mortality Weekly Report, 48(11):228-229.

Arrouji A, Lasfar ZB, Makni K, 1991. Rabies diagnostic laboratory. Institut Pasteur de Tunis. Report. Archives de l'Institut Pasteur de Tunis, 68(1-2):89-95.

Ata FA, Tageldin MH, Al-Sumry HS, Al-Ismaily SI, 1993. Rabies in the Sultanate of Oman. Veterinary Record, 132(3):68-69; 4 ref.

Baer GM, 1991. The natural history of rabies. 2nd Edition. The natural history of rabies. 2nd Edition., 620 pp.; many ref.

Barnard BJH, Voges SF, 1982. A simple technique for the diagnosis of rabies in formalin-preserved brain. Ondersterpoort Journal of Veterinary Research, 49:193-194.

Barrat J, 1992. Experimental diagnosis of rabies. Adaptions to field and tropical conditions. Proceedings of the International Conference on Epidemiology Control and Prevention of Rabies in Eastern and Southern Africa, Lusaka, Zambia, June 2-5. 1992., 72-83; 10 ref.

Barrat J, Barrat MJ, Picard M, Aubert MFA, 1988. Diagnosis of rabies on cell culture: comparison of the results of inoculation of a murine neuroblastoma cell line and mouse inoculation. Comparative Immunology, Microbiology and Infectious Diseases, 11(3-4):207-214; 19 ref.

Basheer AM, Ramakrishna J, Manickam R, 1997. Evaluation of post-exposure vaccination against rabies in cattle. Microbiologica, 20(3):289-294; 11 ref.

Binepal Y, 1992. Rabies in Kenya. Proceedings of the International Conference on Epidemiology Control and Prevention of Rabies in Eastern and Southern Africa, Lusaka, Zambia, June 2-5. 1992., 14-16; 4 ref.

Bingham J, 1992. Rabies in Zimbabwe. Proceedings of the International Conference on Epidemiology Control and Prevention of Rabies in Eastern and Southern Africa, Lusaka, Zambia, June 2-5. 1992., 29-33.

Bishop G, 1992. Rabies in South Africa. Proceedings of the International Conference on Epidemiology Control and Prevention of Rabies in Eastern and Southern Africa, Lusaka, Zambia, June 2-5. 1992., 47-50.

Bishop GC, Durrheim DN, Kloeck PE, Godlonton JD, Bingham J, Speare R, the Rabies Advisory Group, 2003. Rabies guide for the medical, veterinary and allied professions. Pretoria, South Africa: Republic of South Africa Department of Agriculture and Department of Health, 82 pp. http://www.agric.za/docs/GenPub/rabiesB5

Blancou J, 1998. Surveillance and prophylaxis of animal rabies in the world. Bulletin de la Société de Pathologie Exotique, 91(2):123-126; 7 ref.

Blancou J, Baltazar RS, Molli I, Stoltz JF, 1991. Effective postexposure treatment of rabies-infected sheep with rabies immune globulin and vaccine. Vaccine, 9(6):432-437; 27 ref.

Borowka J, 1994. Results of meat hygiene statistics for Germany in 1992. Fleischwirtschaft, 74(3):330.

Brochier B, Dechamps P, Costy F, Chalon P, Hallet L, Peharpre D, Mosselmans F, Beier R, Lecomte L, Mullier P, Roland H, Bauduin B, Renders C, Pastoret PP, 1998. Epidemiological surveillance of rabies in Belgium: 1997 assessment. Annales de Médecine Vétérinaire, 142(4):261-270; 12 ref.

Coertse J, Weyer J, Nel LH, Markotter W, 2010. Improved PCR methods for detection of African rabies and rabies-related lyssaviruses. Journal of Clinical Microbiology, 48(11):3949-3955. http://jcm.asm.org/cgi/content/short/48/11/3949

Delpietro HA, Nader AJ, 1989. Rabies of herbivores transmitted by vampire bats in north-eastern Argentina. Revue Scientifique et Technique - Office International des épizooties, 8(1):177-198; 22 ref.

Delpietro HA, Russo G, Alli C, Patire J, 1991. A new method of controlling vampire bats. Veterinaria Argentina, 8(77):455-458, 460-463; 13 ref.

Delpietro HA, Russo RG, 1996. Ecological and epidemiological aspects of attacks by vampire bats in relation to paralytic rabies in Argentina, and an analysis of proposals for control. Revue Scientifique et Technique - Office International des épizooties, 15(3):971-984; 31 ref.

Depner K, 1992. Rabies in Namibia. Proceedings of the International Conference on Epidemiology Control and Prevention of Rabies in Eastern and Southern Africa, Lusaka, Zambia, June 2-5. 1992., 39-42; 5 ref.

Dias P, 1992. Rabies in Mozambique. Proceedings of the International Conference on Epidemiology Control and Prevention of Rabies in Eastern and Southern Africa, Lusaka, Zambia, June 2-5. 1992., 24-25.

Diaz AM, Papo S, Rodriguez A, Smith JS, 1994. Antigenic analysis of rabies-virus isolates from Latin America and the Caribbean. Journal of Veterinary Medicine. Series B, 41(3):153-160; 11 ref.

Dufour B, Aubert M, Bonnel A, Toma B, 1989. Control of rabies in cattle in 1987: costs and benefits. Point Vétérinaire, 21(122):39-44; 3 ref.

Ettinger SJ, Feldman EC, 2000. Textbook of veterinary internal medicine: diseases of the dog and cat, Volumes 1 and 2, Ed. 5. Philadelphia, USA: W.B. Saunders, 1996 pp.

Feital ASS, Confalonieri UEC, 1998. Epidemiological study of bovine rabies in the State of Rio de Janeiro, Brazil (1980-1992). Revista brasileira de Ciência Veterinária, 5(1):21-27; 7 ref.

Flores-Crespo R, Castro-Quiroz E, Avila-Figueroa D, Flores-Rodriguez J, 1989. Epidemiological study of rabies in cattle transmitted by vampire bats in the Zacapa Department of Guatemala (in Spanish). Tecnica Pecuaria en Mexico, 27(2):97-100.

Fooks AR, Johnson N, Freuling CM, Wakeley PR, Banyard AC, McElhinney LM, Marston DA, Dastjerdi A, Wright E, Weiss RA, Müller T, 2009. Emerging technologies for the detection of rabies virus: challenges and hopes in the 21st century. PLoS Neglected Tropical Diseases, 3(9):e530. http://www.plosntds.org/article/info%3Adoi%2F10.1371%2Fjournal.pntd.0000530

Genovese MA, Andral L, 1978. Comparaison de deux techniques utilisées pour le diagnostic de la rage: l' immunofluorescence et l' immunoperoxydase. Recuel de Medecine Veterinaire, 154(7-8):667-671.

Groushko IV, 1993. Rabies in Moldova in 1992. Rabies Bulletin Europe, 17(1):11.

Gylys L, Chomel BB, Gardner IA, 1998. Epidemiological surveillance of rabies in Lithuania from 1986 to 1996. Revue Scientifique et Technique - Office International des épizooties, 17(3):691-698; 19 ref.

Hameid OA, 1991. Rabies in Sudan: an epidemiological review. Veterinary Record, 128(3):61-62; 4 ref.

He Xianhi, Sun JiaDong, Gao YongZhen, Pan JingYi, Qu ShunHua, 1993. 54 cases of rabies in buffaloes without dog bites. Chinese Journal of Veterinary Medicine, 19(4):31.

Hostnik P, Zeleznik Z, Tomasic A, 1994. Control of rabies in Slovenia. Veterinarski Arhiv, 64(1/3):13-17; 8 ref.

Hou KC, 1992. Report of suspected cases of rabies in pigs. Chinese Journal of Veterinary Medicine, 18(7):22, 28.

Illango J, 1992. Rabies in Uganda. Proceedings of the International Conference on Epidemiology Control and Prevention of Rabies in Eastern and Southern Africa, Lusaka, Zambia, June 2-5. 1992., 9-13.

Ito N, Sugiyama M, Oraveerakul K, Piyaviriyakul P, Lumlertdacha B, Arai YT, Tamura Y, Mori Y, Minamoto N, 1999. Molecular epidemiology of rabies in Thailand. Microbiology and Immunology, 43(6):551-559; 21 ref.

Jacobo RA, González JA, Yanez EA, Stamatti GM, Fleitas F, 1998. An outbreak of rabies in vampire bats in the Northwest of the Province of Corrientes, Argentina. Revista de Medicina Veterinaria (Buenos Aires), 79(4):294-296; 12 ref.

Jaramillo Arango CJ, Martínez Maya JJ, 1998. Epidemiological evaluation of bovine paralytic rabies in Mexico during the period, 1986-1995. Técnica Pecuaria en México, 36(2):109-120; 24 ref.

Jenkins SR(NASPHV Chair), 1998. Compendium of animal rabies control, 1998. Morbidity and Mortality Weekly Report, RR-9:9 ref.

Jindal N, Narang G, 1998. An outbreak of rabies in buffaloes in Haryana. Indian Veterinary Journal, 75(9):839-840; 3 ref.

Kandavel E, Appaji Rao VN, Nedunchelliyan S, 1989. Rabies in calves. Indian Journal of Animal Health, 28(1):73-74; 7 ref.

Kang B, Oh J, Lee C, Park BK, Park Y, Hong K, Lee K, Cho B, Song D, 2007. Evaluation of a rapid immunodiagnostic test kit for rabies virus. Journal Virology Methods, 145:30-36.

Kavishe TS, 1988. Country report on animal health. Tanzania. Animal health problems in selected African countries. Report of a technical consultation in Lusaka, Zambia, 23-28 November 1987., 85-97; [Arbetsrapport 91].

Kerekes B, 1997. Recent data on the incidence of rabies in Hungary. Magyar állatorvosok Lapja, 119(5):290-293.

Khomari L, 1992. Rabies in Lesotho. Proceedings of the International Conference on Epidemiology Control and Prevention of Rabies in Eastern and Southern Africa, Lusaka, Zambia, June 2-5. 1992., 45-46.

Kieny MP, Lathe R, Drillien R, Spehner D, Skory S, Schmitt D, Wiktor T, Koprowski H, Lecocq JP, 1984. Expression of rabies virus glycoprotein from a recombinant vaccinia virus. Nature, UK, 312(5990):163-166.

Kim JaeHoon, Hwang EuiKyung, Sohn HyunJoo, Bae YouChan, Yoon YongDhuk, 1995. Recent occurrence of rabies in Korea Republic (1993-1994). RDA Journal of Agricultural Science, Veterinary, 37(1):508-518; 33 ref.

Kociorski A, 1994. Rabies in a sow. Magazyn Weterynaryjny, 3(1):70; 2 ref.

Kovalev NA, Usenya MM, 1996. Epidemiology and prevention of rabies in Belarus. Veterinarnaya nauka - proizvodstvu, No.:9-15.

Krebs JW, Smith JS, Rupprecht CE, Childs JE, 1998. Rabies surveillance in the United States during 1997. Journal of the American Veterinary Medical Association, 213(12):1713-1728; 32 ref.

Krebs JW, Smith JS, Rupprecht CE, Childs JE, 1999. Rabies surveillance in the United States during 1998. Journal of the American Veterinary Medical Association, 215(12):1786-1798; 34 ref.

Kulonen K, Boldina I, 1993. Differentiation of two rabies strains in Estonia with reference to recent Finnish isolates. Journal of Wildlife Diseases, 29(2):209-213; 20 ref.

Lagacé F, 1998. The history of rabies in Quebec from 1958 to 1997. Médecin Vétérinaire du Québec, 28(3):106-110; 22 ref.

Lau HD, 1990. Common buffalo diseases in Amazonian Brazil. Buffalo Bulletin, 9(4):75-77.

Lembo T, Hampson K, Kaare MT, Ernest E, Knobel D, Kazwala RR, Haydon DT, Cleaveland S, 2010. The feasibility of canine rabies elimination in Africa: dispelling doubts with data. PLoS Neglected Tropical Diseases, 4(2):e626. http://www.plosntds.org/article/info%3Adoi%2F10.1371%2Fjournal.pntd.0000626

Leupold U, Martig J, Vendevelde M, 1989. Diagnostic aspects of neurological diseases in cattle. A retrospective study. Schweizer Archiv für Tierheilkunde, 131(6):327-340; 33 ref.

Lis H, 1999. Epidemiology of rabies in Poland, after 6 years of vaccinating foxes. Medycyna Weterynaryjna, 55(10):665-668; 8 ref.

Logan NA, 1988. Bacillus species of medical and veterinary importance. Journal of Medical Microbiology, 25(3):157-165; 46 ref.

Mandelík R, Chvojka D, Grajdos V, Banai G, 1997. Rabies in the Kosice area of Slovakia in the period 1993-1995. Stabilization of the infection or a positive effect of prevention. Slovensky Veterinársky Casopis, 22(2):120-121.

Masupu K, 1992. Rabies in Botswana. Proceedings of the International Conference on Epidemiology Control and Prevention of Rabies in Eastern and Southern Africa, Lusaka, Zambia, June 2-5. 1992., 34-38.

Mattos CAde, Mattos CCde, Smith JS, Miller ET, Papo S, Utrera A, Osburn BI, 1996. Genetic characterization of rabies field isolates from Venezuela. Journal of Clinical Microbiology, 34(6):1553-1558; 23 ref.

Mól H, 1999. Epidemiology of rabies in 1997 in Poland. Zycie Weterynaryjne, 74(2):77-78.

Montaño Hirose JA, Bourhy H, Sureau P, 1991. Retro-orbital route for brain specimen collection for rabies diagnosis. Veterinary Record, 129(13):291-292.

Morse DL, Shayegani M, Gallo RJ, 1984. Epidemiologic investigation of a Yersinia camp outbreak linked to a food handler. American Journal of Public Health, 74(6):589-592; 18 ref.

Morvan J, 1992. Rabies in Madagascar. Proceedings of the International Conference on Epidemiology Control and Prevention of Rabies in Eastern and Southern Africa, Lusaka, Zambia, June 2-5. 1992., 26-28.

Muller WW, Cox JH, Hohnsbeen KP, 1999. Summary of rabies in Europe [April-June 1999]. Rabies Bulletin Europe, 23(2):3-9.

Muriuki SK, Wandera JG, Njenga MJ, Mutiga ER, Thaiyah A, Njagi ON, Muturi AM, 1994. An outbreak of rabies in a dairy farm in Kiambu district, Kenya. Bulletin of Animal Health and Production in Africa, 42(3):265-266; 11 ref.

Mweene AS, Pandey GS, Sinyangwe P, Nambota A, Samui K, Kida H, 1996. Viral diseases of livestock in Zambia. Japanese Journal of Veterinary Research, 44(2):89-105; 77 ref.

Mwiyeriwa C, 1992. Rabies in Malawi. Proceedings of the International Conference on Epidemiology Control and Prevention of Rabies in Eastern and Southern Africa, Lusaka, Zambia, June 2-5. 1992., 22-23.

OIE Handistatus, 2002. World Animal Health Publication and Handistatus II (dataset for 2001). Paris, France: Office International des Epizooties.

OIE Handistatus, 2003. World Animal Health Publication and Handistatus II (dataset for 2002). Paris, France: Office International des Epizooties.

OIE Handistatus, 2004. World Animal Health Publication and Handistatus II (data set for 2003). Paris, France: Office International des Epizooties.

OIE, 2005. World Animal Health Publication and Handistatus II (data set for 2004). Paris, France: Office International des Epizooties.

OIE, 2009. World Animal Health Information Database - Version: 1.4. World Animal Health Information Database. Paris, France: World Organisation for Animal Health. http://www.oie.int

OIE, 2012. World Animal Health Information Database. Version 2. World Animal Health Information Database. Paris, France: World Organisation for Animal Health. http://www.oie.int/wahis_2/public/wahid.php/Wahidhome/Home

Ostrowska JD, Hermanowska-Szpakowicz T, 1997. Prevention of rabies in man. Medycyna Weterynaryjna, 53(3):144-147; 14 ref.

Owoyele GD, 1992. Rabies outbreak in Thimphu, Bhutan. Bhutan Journal of Animal Husbandry, 13(APRIL):36-39; 3 ref.

Pastoret PP, Brochier B, 1999. Epidemiology and control of fox rabies in Europe. Vaccine, 17(13/14):1750-1754; 35 ref.

Perrin P, Lafon M, Versmisse P, Sureau P, 1985. Application d'une méthode immunoenzymatique au titrage des anticorps antirabiques neutralisants en cultures cellulaires. J. Biol. Stand., 13:35-42.

Pessôa Silva MC, Moreira EC, Inzaurralde AL, Modena CM, 1996. Land use as a determinant for the prevalence of bovine rabies in the north of Minas Gerais, Brazil. Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 48(3):265-274; 16 ref.

Plaza MN, Pérez Barrientos M, Pascal PE, Elejalde L, Avila J, 1997. Bovine rabies in Venezuela during the period 1983-1992. Revista Cientifica, Facultad de Ciencias Veterinarias, Universidad del Zulia, 7(2):111-122; 28 ref.

Polyushkina GS, Gorkunov AA, 1998. Epizootiology and approaches for improvement of rabies in the Moscow region. Voprosy Virusologii, 43(1):47-48; 12 ref.

Qian AiDong, Hou ShiKuan, He ZhaoYang, Li HongWei, Tu ChangChun, Yin Zhen, 1998. Sequencing of glycoprotein ectodomain gene of rabies street viruses from different animals in China. Chinese Journal of Virology, 14(3):262-267; 16 ref.

Rehman AU, Rizvi AUR, Ajmal M, 1988. Occurrence of rabies virus in the saliva of apparently healthy dogs in Lahore. Pakistan Journal of Zoology, 20(2):173-176; 20 ref.

Roehe PM, Pantoja LD, Shaefer R, Nardi NB, King AA, 1997. Analysis of Brazilian rabies virus isolates with monoclonal antibodies to Lyssavirus antigens. Revista de Microbiologia, 28(4):288-292; 27 ref.

Rukavina L, Nevjestic A, Hadzimuratovic M, 1991. Animal disease occurrence in Bosnia and Hercegovina in the period 1981-1990. Veterinaria (Sarajevo), 40(1-2):3-15; 1 ref.

Sald Fernández S, Flores-Crespo R, 1991. Control of the common vampire (Desmodus rotundus) with diphenadione applied to cattle by the intramuscular route. Veterinaria México, 22(2):165-168; 8 ref.

Salem SAH, El-Mashed I, Hamoda FK, 1995. Pathological and epidemiological studies on bovine rabies in Kaluobia Governorate. Proceedings of the Third Scientific Congress Egyptian Society for Cattle Diseases, Volume 2. 3-5 December 1995 Assiut - Egypt, 303-311; 28 ref.

Schulz W, 1989. Rabies in cattle, epidemiology and clinical features. Monatshefte für Veterinärmedizin, 44(6):201-204; 39 ref.

Separovic S, Kovac Z, Schluter H (ed.), Maurer J, 1997. The current epizootiological situation and immunoprophylaxis of rabies in animals in Republic of Croatia. WHO conference on oral immunization of foxes against rabies in Central and Eastern Europe, 1996. Proceedings Portoroz, Slovenia, 44-46.

Sihvonen L, Kulonen K, Neuvonen E, 1994. Immunization of cattle against rabies using inactivated cell culture vaccines. Acta Veterinaria Scandinavica, 35(4):371-376; 8 ref.

Singh CK, Grewal GS, 1998. Comparative evaluation of rabies diagnostic sensitivity among seven laboratory techniques. Indian Journal of Animal Sciences, 68(12):1210-1213; 29 ref.

Singh CK, Grewal GS, 1998. Progressive spread of rabies viral antigen in central nervous system of infected buffalo calves. Indian Journal of Animal Sciences, 68(12):1255-1257; 16 ref.

Singh KB, Singh PJ, Singh CK, 1999. Rabies in buffaloes - a clinical report. Indian Veterinary Journal, 76(1):52-53; 4 ref.

Sinyangwe P, 1992. Rabies in Zambia. Proceedings of the International Conference on Epidemiology Control and Prevention of Rabies in Eastern and Southern Africa, Lusaka, Zambia, June 2-5. 1992., 19-21; [aka, Zambia, June 2-5. 1992.].

Smith JS, Yager PA, Baer GC, 1973. A rapid reproducible test for determining rabies neutralizing antibody. Bulletin of WHO, 48:535-541.

Stoltenow CL, Shirely LA, Jones T, Rupprecht CE, 1999. Clinical report - atypical rabies in a cow. Bovine Practitioner, 33(1):4-5; 10 ref.

Swanepoel R, Barnard BJH, Meredith CD, Bishop GC, Brückner GK, Foggin CM, Hübschle OJB, 1993. Rabies in southern Africa. Onderstepoort Journal of Veterinary Research, 60(4):325-346.

Tanyi J, Porkoláb L, Fenyvesi A, Földi J, 1988. Observations on the clinical signs, epidemiology and differential diagnosis of rabies in cattle. Magyar állatorvosok Lapja, 43(7):407-413; 25 ref.

Tariq WUZ, Shafi MS, Jamal S, Ahmad M, 1991. Rabies in man handling infected calf. Lancet (British Edition), 337(8751):1224; 1 ref.

Thakuri KC, Mahato SN, Thakur RP, 1992. Diseases of cattle and buffaloes in the Koshi hills of Nepal. A retrospective study. Veterinary Review (Kathmandu), 7(2):41-46; 8 ref.

Umoh JU, Blenden DC, 1981. Immunofluorescent staining of rabies virus antigen in formalin fixed tissue after treatment with trypsin. Bulletin of WHO, 59(5):737-744.

Valtchovski R, 1995. Rabies in Bulgaria from 1984-1994. Rabies Bulletin Europe, 19(1):12-13.

Vargas-Garcia R, Cardenas-Lara J, 1996. Epidemiology of rabies: current situation in Mexico (in Spanish). Ciencia Veterinaria, 7:331-360.

Vörös K, Tanyi J, Karsai F, 1999. Clinical experiences with rabies in cattle in Hungary. Deutsche Tierärztliche Wochenschrift, 106(1):46-48; 5 ref.

Webster WA, Casey GA, Charlton KM, 1989. Bat-induced rabies in terrestrial mammals in Nova Scotia and Newfoundland. Canadian Veterinary Journal, 30(8):679; 2 ref.

WHO Collaborating Centre for Rabies Surveillance & Research, 1996. Summary of rabies in Europe [April-June 1996; including reports from individual countries]. Rabies Bulletin Europe, 20(2):3-9.

World Health Organization, 1989. Fox rabies. Prophylaxis of fox rabies: a cost-benefit study. Weekly Epidemiological Record, 64(25):189-192; [Based on a record from l'Entente interdépartementale de Lutte contre la Rage et du Centre National d'Etudes la Rage.].

World Health Organization, 1992. Wildlife rabies in Oman and the United Arab Emirates. Weekly Epidemiological Record, 67(10):65-68.

World Health Organization, 1998. Animal rabies, Denmark. Bat virus causes rabies in sheep. Weekly Epidemiological Record, 73(41):320.

Zalan E, Wilson C, Pukitis, 1979. A microtest for quantitation of rabies virus. J. Biol. Stand., 7:213-220.

Zeller G, Kant J, Lötsch D, 1989. Risk to human beings of rabies-infected sheep and cats. Monatshefte für Veterinärmedizin, 44(6):191-193; 21 ref.

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Links to Websites

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OIE Reference Experts and Laboratories

(http://www.oie.int, accessed 5 June 2013)

Dr Christine Fehlner-Gardiner
Centre of Expertise for Rabies CFIA/ACIA
Ottawa Laboratory Fallowfield
Animal Diseases Research Institute
3851 Fallowfield Road
P.O. Box 11300
Station H
Nepean, Ontario K2H 8P9
CANADA
Tel: +1-343 212 03 04 Fax: +1-343 212 02 02
Email: This email address is being protected from spambots. You need JavaScript enabled to view it.

Prof. Changchun Tu
Diagnostic Laboratory for Rabies and Wildlife Associated Zoonoses
Department of Virology
Changchun Veterinary Research Institute (CVRI)
Chinese Academy of Agricultural Sciences (CAAS)
Liuying Xi Road 666
Jingyue Economic Development Zone
Changchun 130122
CHINA (PEOPLE'S REP. OF)
Tel: +86-431 86 98 59 21 Fax: +86-431 86 98 58 62
Email: This email address is being protected from spambots. You need JavaScript enabled to view it.

Dr Jacques Barrat (1)
Agence nationale de Sécurité Sanitaire de l'Alimentation, de l'Environnement et du Travail (Anses)
Laboratoire de la faune sauvage de Nancy
Technopôle agricole et vétérinaire
B.P. 40009
54220 Malzéville Cedex
FRANCE
Tel: +33 (0)3 83 29 89 50 Fax: +33 (0)3 83 29 89 58
Email: This email address is being protected from spambots. You need JavaScript enabled to view it.

Dre Florence Cliquet (2)
Agence Nationale de Sécurité Sanitaire de l'Alimentation, de l'Environnement et du Travail
(Anses)
Laboratoire de la faune sauvage de Nancy
Domaine de Pixérécourt
B.P. 9
54220 Malzéville Cedex
FRANCE
Tel: +33 (0)3 83 29 89 50 Fax: +33 (0)3 83 29 89 58
Email: This email address is being protected from spambots. You need JavaScript enabled to view it.

Dr Thomas Müller
Institute for Epidemiology, Friedrich-Loeffler Institut
Federal Research Institute for Animal Health
Seestr. 55
D-16868 Wusterhausen/Dosse
GERMANY
Tel: +49-33 97 98 01 86 Fax: +49-33 97 98 02 00
Email: This email address is being protected from spambots. You need JavaScript enabled to view it.

Dr Dong-Kun Yang
Rabies Research Laboratory
Division of Viral Disease
Animal Plant and Fisheries Quarantine and Inspection Agency
Ministry of Food, Agriculture, Forestry and Fisheries
175 Anyang-ro, Manan-gu
Anyang, Gyeongii 430-757
KOREA (REP. OF)
Tel: +82 31 467.1783 Fax: +82 31 467.1797
Email: This email address is being protected from spambots. You need JavaScript enabled to view it.

Dr Claude Taurai Sabeta
Onderstepoort Veterinary Institute
Rabies Unit
Private Bag X05
Onderstepoort 0110
SOUTH AFRICA
Tel: +27-12 529 94 39 Fax: +27-12 529 93 90
Email: This email address is being protected from spambots. You need JavaScript enabled to view it.

Dr Anthony Fooks
Rabies and Widlife Zoonoses Group
Virology Department
Animal Health and Veterinary Laboratories Agency
New Haw, Addlestone
Surrey KT15 3NB
Weybridge
UNITED KINGDOM
Tel: +44-1932 35.78.40 Fax: +44-1932 35.72.39
Email: This email address is being protected from spambots. You need JavaScript enabled to view it.

Dr Richard Franka
Poxvirus and Rabies Branch
Division of High-Consequence Pathogens and Pathology
National Center for Emerging and Zoonotic Infectious Diseases
Centers for Disease Control and Prevention
1600 Clifton Road, NE, Mail Stop G33
Atlanta, GA 30 333
UNITED STATES OF AMERICA
Tel: +1-404 639.10.50 Fax: +1-404 639.15.64
Email: This email address is being protected from spambots. You need JavaScript enabled to view it.

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Images


 Furious stage of rabies in cattle: Salivation, dropped lower jaw and strabismus can be seen on this highly excited rabid cow. Whilst pressing its head onto the fence it was producing a highly abnormal bellowing sound. © Károly Vörös/Department of Internal Medicine, University of Veterinary Science, Budapest.Furious stage of rabies in cattle: Salivation, dropped lower jaw and strabismus can be seen on this highly excited rabid cow. Whilst pressing its head onto the fence it was producing a highly abnormal bellowing sound. © Károly Vörös/Department of Internal Medicine, University of Veterinary Science, Budapest.

 

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Date of report: 03/06/2013

© CAB International 2013. Distributed under license by African Union – Interafrican Bureau for Animal Resources.

Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License.